I prefer to nest by the window, however- this makes me avoid intaking liquids, so I don't have to bother others. I've had to wake people in the past to get out- awkward!
Even awkwarder when someone pulled their legs in for me to squeeze through- at the same time the person in the seat in front decided to recline their seat- I was plunged forward, face (actually chest!) first, landing straddled over them. Needless to say my seat choice for a few flights after that was the aisle!...I'm currently doing the universal gesture for shame at the thought .